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» Current approaches to gene regulatory network modelling
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TSP
2010
13 years 3 months ago
Selection policy-induced reduction mappings for Boolean networks
Developing computational models paves the way to understanding, predicting, and influencing the long-term behavior of genomic regulatory systems. However, several major challenges ...
Ivan Ivanov, Plamen Simeonov, Noushin Ghaffari, Xi...
BMCBI
2010
152views more  BMCBI 2010»
13 years 8 months ago
Comparative study of three commonly used continuous deterministic methods for modeling gene regulation networks
Background: A gene-regulatory network (GRN) refers to DNA segments that interact through their RNA and protein products and thereby govern the rates at which genes are transcribed...
Martin T. Swain, Johannes J. Mandel, Werner Dubitz...
ECAL
2005
Springer
14 years 2 months ago
Biological Development of Cell Patterns: Characterizing the Space of Cell Chemistry Genetic Regulatory Networks
Abstract. Genetic regulatory networks (GRNs) control gene expression and are responsible for establishing the regular cellular patterns that constitute an organism. This paper intr...
Nicholas S. Flann, Jing Hu, Mayank Bansal, Vinay P...
BIBE
2008
IEEE
111views Bioinformatics» more  BIBE 2008»
13 years 10 months ago
Structure learning for biomolecular pathways containing cycles
Bayesian network structure learning is a useful tool for elucidation of regulatory structures of biomolecular pathways. The approach however is limited by its acyclicity constraint...
S. Itani, Karen Sachs, Garry P. Nolan, M. A. Dahle...
CIBCB
2006
IEEE
14 years 2 months ago
A Systematic Computational Approach for Transcription Factor Target Gene Prediction
— Computational prediction of transcription factor’s binding sites and regulatory target genes has great value to the biological studies of cellular process. Existing practices...
Ji He, Xinbin Dai, Xuechun Zhao