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» Current approaches to gene regulatory network modelling
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TFS
2010
152views Education» more  TFS 2010»
13 years 3 months ago
Robust Optimal Reference-Tracking Design Method for Stochastic Synthetic Biology Systems: T-S Fuzzy Approach
At present, the development in the nascent field of synthetic gene networks is still difficult. Most newly created gene networks are nonfunctioning due to intrinsic parameter fluct...
Bor-Sen Chen, Chih-Hung Wu
BMCBI
2008
201views more  BMCBI 2008»
13 years 8 months ago
A copula method for modeling directional dependence of genes
Background: Genes interact with each other as basic building blocks of life, forming a complicated network. The relationship between groups of genes with different functions can b...
Jong-Min Kim, Yoon-Sung Jung, Engin A. Sungur, Kap...
BMCBI
2006
133views more  BMCBI 2006»
13 years 8 months ago
Topological basis of signal integration in the transcriptional-regulatory network of the yeast, Saccharomyces cerevisiae
Background: Signal recognition and information processing is a fundamental cellular function, which in part involves comprehensive transcriptional regulatory (TR) mechanisms carri...
Illés J. Farkas, Chuang Wu, Chakra Chennubh...
CMSB
2010
Springer
13 years 3 months ago
Action-based analysis of discrete regulatory networks with short-term stimuli
To incorporate instant effects and different timescales within a single biological system, an extension of discrete regulatory networks with short-term stimuli is proposed. By mai...
Christian Krause, Carola Krause, Erik P. de Vink
BMCBI
2010
183views more  BMCBI 2010»
13 years 5 months ago
The complexity of gene expression dynamics revealed by permutation entropy
Background: High complexity is considered a hallmark of living systems. Here we investigate the complexity of temporal gene expression patterns using the concept of Permutation En...
Xiaoliang Sun, Yong Zou, Victoria J. Nikiforova, J...