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» Current approaches to gene regulatory network modelling
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EDBT
2009
ACM
241views Database» more  EDBT 2009»
14 years 3 months ago
GADDI: distance index based subgraph matching in biological networks
Currently, a huge amount of biological data can be naturally represented by graphs, e.g., protein interaction networks, gene regulatory networks, etc. The need for indexing large ...
Shijie Zhang, Shirong Li, Jiong Yang
WABI
2010
Springer
167views Bioinformatics» more  WABI 2010»
13 years 6 months ago
Quantifying the Strength of Natural Selection of a Motif Sequence
Quantification of selective pressures on regulatory sequences is a central question in studying the evolution of gene regulatory networks. Previous methods focus primarily on sing...
Chen-Hsiang Yeang
ECAI
2008
Springer
13 years 10 months ago
Temporal Logic Patterns for Querying Qualitative Models of Genetic Regulatory Networks
Formal verification based on model checking provides a powerful technology to query qualitative models of dynamical systems. The application of model-checking approaches is hamper...
Pedro T. Monteiro, Delphine Ropers, Radu Mateescu,...
ICASSP
2011
IEEE
13 years 5 days ago
Uncover cooperative gene regulations by microRNAs and transcription factors in glioblastoma using a nonnegative hybrid factor mo
—Transcriptional regulation by transcription factors (TFs) and microRNAs controls when and how much RNA is created. Due to technical limitations, the protein level expressions of...
Jia Meng, Hung-I Harry Chen, Jianqiu Zhang, Yidong...
CEC
2003
IEEE
14 years 1 months ago
Transcription and evolution of a virtual bacteria culture
Abstract- This paper describes implementation details and results from a simulated multi-agent bacteria ecosystem. Each bacterium is encoded on a DNA-like genome, specifying the ge...
Ricardo M. Hoar, Joanne K. Penner, Christian Jacob