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» Current approaches to gene regulatory network modelling
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BMCBI
2007
167views more  BMCBI 2007»
13 years 6 months ago
A stochastic differential equation model for transcriptional regulatory networks
Background: This work explores the quantitative characteristics of the local transcriptional regulatory network based on the availability of time dependent gene expression data se...
Adriana Climescu-Haulica, Michelle D. Quirk
BIOCOMP
2006
13 years 8 months ago
Dynamic Bayesian Network (DBN) with Structure Expectation Maximization (SEM) for Modeling of Gene Network from Time Series Gene
Exploring gene regulatory network is a key topic in molecular biology. In this paper, we present a new dynamic Bayesian network (DBN) framework embedded with structural expectatio...
Yu Zhang, Zhidong Deng, Hongshan Jiang, Peifa Jia
GECCO
2005
Springer
178views Optimization» more  GECCO 2005»
14 years 7 days ago
A co-evolutionary hybrid algorithm for multi-objective optimization of gene regulatory network models
In this paper, the parameters of a genetic network for rice flowering time control have been estimated using a multiobjective genetic algorithm approach. We have modified the rece...
Praveen Koduru, Sanjoy Das, Stephen Welch, Judith ...
CIBB
2009
13 years 7 months ago
On the Use of Temporal Formal Logic to Model Gene Regulatory Networks
Modelling activities in molecular biology face the difficulty of prediction to link molecular knowledge with cell phenotypes. Even when the interaction graph between molecules is k...
Gilles Bernot, Jean-Paul Comet
BMCBI
2011
12 years 10 months ago
A mutation degree model for the identification of transcriptional regulatory elements
Background: Current approaches for identifying transcriptional regulatory elements are mainly via the combination of two properties, the evolutionary conservation and the overrepr...
Changqing Zhang, Jin Wang, Xu Hua, Jinggui Fang, H...