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» DBAli tools: mining the protein structure space
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BMCBI
2006
159views more  BMCBI 2006»
13 years 7 months ago
MultiSeq: unifying sequence and structure data for evolutionary analysis
Background: Since the publication of the first draft of the human genome in 2000, bioinformatic data have been accumulating at an overwhelming pace. Currently, more than 3 million...
Elijah Roberts, John Eargle, Dan Wright, Zaida Lut...
NAR
2011
257views Computer Vision» more  NAR 2011»
12 years 10 months ago
The STRING database in 2011: functional interaction networks of proteins, globally integrated and scored
An essential prerequisite for any systems-level understanding of cellular functions is to correctly uncover and annotate all functional interactions among proteins in the cell. To...
Damian Szklarczyk, Andrea Franceschini, Michael Ku...
BMCBI
2010
137views more  BMCBI 2010»
13 years 7 months ago
Improving pairwise sequence alignment accuracy using near-optimal protein sequence alignments
Background: While the pairwise alignments produced by sequence similarity searches are a powerful tool for identifying homologous proteins - proteins that share a common ancestor ...
Michael L. Sierk, Michael E. Smoot, Ellen J. Bass,...
KAIS
2000
87views more  KAIS 2000»
13 years 7 months ago
An Index Structure for Data Mining and Clustering
Abstract. In this paper we present an index structure, called MetricMap, that takes a set of objects and a distance metric and then maps those objects to a k-dimensional space in s...
Xiong Wang, Jason Tsong-Li Wang, King-Ip Lin, Denn...
ICDM
2005
IEEE
188views Data Mining» more  ICDM 2005»
14 years 1 months ago
Hierarchy-Regularized Latent Semantic Indexing
Organizing textual documents into a hierarchical taxonomy is a common practice in knowledge management. Beside textual features, the hierarchical structure of directories reflect...
Yi Huang, Kai Yu, Matthias Schubert, Shipeng Yu, V...