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» DIG - a system for gene annotation and functional discovery
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BMCBI
2005
100views more  BMCBI 2005»
13 years 7 months ago
Speeding disease gene discovery by sequence based candidate prioritization
Background: Regions of interest identified through genetic linkage studies regularly exceed 30 centimorgans in size and can contain hundreds of genes. Traditionally this number is...
Euan A. Adie, Richard R. Adams, Kathryn L. Evans, ...
BMCBI
2006
249views more  BMCBI 2006»
13 years 7 months ago
Gene functional similarity search tool (GFSST)
Background: With the completion of the genome sequences of human, mouse, and other species and the advent of high throughput functional genomic research technologies such as biomi...
Peisen Zhang, Jinghui Zhang, Huitao Sheng, James J...
BMCBI
2008
111views more  BMCBI 2008»
13 years 7 months ago
Information-based methods for predicting gene function from systematic gene knock-downs
Background: The rapid annotation of genes on a genome-wide scale is now possible for several organisms using high-throughput RNA interference assays to knock down the expression o...
Matthew T. Weirauch, Christopher K. Wong, Alexandr...
BMCBI
2007
131views more  BMCBI 2007»
13 years 7 months ago
FUNC: a package for detecting significant associations between gene sets and ontological annotations
Background: Genome-wide expression, sequence and association studies typically yield large sets of gene candidates, which must then be further analysed and interpreted. Informatio...
Kay Prüfer, Bjoern Muetzel, Hong Hai Do, Gunt...
BMCBI
2006
186views more  BMCBI 2006»
13 years 7 months ago
Systematic gene function prediction from gene expression data by using a fuzzy nearest-cluster method
Background: Quantitative simultaneous monitoring of the expression levels of thousands of genes under various experimental conditions is now possible using microarray experiments....
Xiaoli Li, Yin-Chet Tan, See-Kiong Ng