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ICASSP
2011
IEEE
12 years 11 months ago
Message-passing for base-calling in sequencing-by-synthesis systems
Performance of DNA sequencing-by-synthesis systems is fundamentally limited by the stochastic nature of the underlying biochemical process. We develop a novel graphical representa...
Sang Hyun Lee, Manohar Shamaiah, Haris Vikalo
GECCO
2005
Springer
124views Optimization» more  GECCO 2005»
14 years 1 months ago
The evolutionary computation approach to motif discovery in biological sequences
Finding motifs — patterns of conserved residues — within nucleotide and protein sequences is a key part of understanding function and regulation within biological systems. Thi...
Michael A. Lones, Andrew M. Tyrrell
DNA
2008
Springer
13 years 9 months ago
A Simple DNA Gate Motif for Synthesizing Large-Scale Circuits
The prospects of programming molecular systems to perform complex autonomous tasks has motivated research into the design of synthetic biochemical circuits. Of particular interest ...
Lulu Qian, Erik Winfree
UC
2005
Springer
14 years 1 months ago
A Computational Model for Self-assembling Flexible Tiles
We present a theoretical model for self-assembling tiles with flexible branches motivated by DNA branched junction molecules. We encode an instance of a “problem” as a pot of ...
Natasa Jonoska, Gregory L. McColm
IJFCS
2007
109views more  IJFCS 2007»
13 years 7 months ago
Computational Power of intramolecular gene Assembly
The process of gene assembly in ciliates, an ancient group of organisms, is one of the most complex instances of DNA manipulation known in any organism. Three molecular operations...
Tseren-Onolt Ishdorj, Ion Petre, Vladimir Rogojin