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13 years 9 months ago
A Practical Algorithm for Optimal Inference of Haplotypes from Diploid Populations
The next phase of human genomics will involve largescale screens of populations for signi cant DNA polymorphisms, notably single nucleotide polymorphisms SNP's. Dense human S...
Dan Gusfield
BMCBI
2007
80views more  BMCBI 2007»
13 years 8 months ago
AT excursion: a new approach to predict replication origins in viral genomes by locating AT-rich regions
Background: Replication origins are considered important sites for understanding the molecular mechanisms involved in DNA replication. Many computational methods have been develop...
David S. H. Chew, Ming-Ying Leung, Kwok Pui Choi
BMCBI
2008
123views more  BMCBI 2008»
13 years 8 months ago
Pol II promoter prediction using characteristic 4-mer motifs: a machine learning approach
Background: Eukaryotic promoter prediction using computational analysis techniques is one of the most difficult jobs in computational genomics that is essential for constructing a...
Firoz Anwar, Syed Murtuza Baker, Taskeed Jabid, Md...
BIB
2006
141views more  BIB 2006»
13 years 8 months ago
Statistical significance in biological sequence analysis
One of the major goals of computational sequence analysis is to find sequence similarities, which could serve as evidence of structural and functional conservation, as well as of ...
Alexander Yu. Mitrophanov, Mark Borodovsky
NCA
2006
IEEE
13 years 8 months ago
Analysing the localisation sites of proteins through neural networks ensembles
Scientists involved in the area of proteomics are currently seeking integrated, customised and validated research solutions to better expedite their work in proteomics analyses and...
Aristoklis D. Anastasiadis, George D. Magoulas