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BMCBI
2010
154views more  BMCBI 2010»
13 years 7 months ago
An eScience-Bayes strategy for analyzing omics data
Background: The omics fields promise to revolutionize our understanding of biology and biomedicine. However, their potential is compromised by the challenge to analyze the huge da...
Martin Eklund, Ola Spjuth, Jarl E. S. Wikberg
BMCBI
2010
163views more  BMCBI 2010»
13 years 7 months ago
DraGnET: Software for storing, managing and analyzing annotated draft genome sequence data
Background: New "next generation" DNA sequencing technologies offer individual researchers the ability to rapidly generate large amounts of genome sequence data at drama...
Stacy Duncan, Ruchita Sirkanungo, Leslie Miller, G...
BMCBI
2010
111views more  BMCBI 2010»
13 years 7 months ago
Dynamic probe selection for studying microbial transcriptome with high-density genomic tiling microarrays
Background: Current commercial high-density oligonucleotide microarrays can hold millions of probe spots on a single microscopic glass slide and are ideal for studying the transcr...
Hedda Høvik, Tsute Chen
BMCBI
2010
110views more  BMCBI 2010»
13 years 7 months ago
On the use of resampling tests for evaluating statistical significance of binding-site co-occurrence
Background: In eukaryotes, most DNA-binding proteins exert their action as members of large effector complexes. The presence of these complexes are revealed in high-throughput gen...
David S. Huen, Steven Russell
BMCBI
2010
86views more  BMCBI 2010»
13 years 7 months ago
An automatic method for identifying surface proteins in bacteria: SLEP
Background: Bacterial infections represent a global health challenge. The identification of novel antibacterial targets for both therapy and vaccination is needed on a constant ba...
Emanuela Giombini, Massimiliano Orsini, Danilo Car...