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    BMCBI
    2006
    103views more  BMCBI 2006»
    Probe-level linear model fitting and mixture modeling results in high accuracy detection of differential gene expression
    13 years 7 months ago
    Probe-level linear model fitting and mixture modeling results in high accuracy detection of differential gene expression
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    Background: The identification of differentially expressed genes (DEGs) from Affymetrix GeneChips arrays is currently done by first computing expression levels from the low-level ...
    Sébastien Lemieux
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    BMCBI
    2006
    128views more  BMCBI 2006»
    Rank-statistics based enrichment-site prediction algorithm developed for chromatin immunoprecipitation on chip experiments
    13 years 7 months ago
    Rank-statistics based enrichment-site prediction algorithm developed for chromatin immunoprecipitation on chip experiments
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    Background: High density oligonucleotide tiling arrays are an effective and powerful platform for conducting unbiased genome-wide studies. The ab initio probe selection method emp...
    Srinka Ghosh, Heather A. Hirsch, Edward A. Sekinge...
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    BMCBI
    2007
    116views more  BMCBI 2007»
    MED: a new non-supervised gene prediction algorithm for bacterial and archaeal genomes
    13 years 7 months ago
    MED: a new non-supervised gene prediction algorithm for bacterial and archaeal genomes
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    Background: Despite a remarkable success in the computational prediction of genes in Bacteria and Archaea, a lack of comprehensive understanding of prokaryotic gene structures pre...
    Huaiqiu Zhu, Gang-Qing Hu, Yi-Fan Yang, Jin Wang, ...
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    BMCBI
    2007
    136views more  BMCBI 2007»
    Prediction of tissue-specific cis-regulatory modules using Bayesian networks and regression trees
    13 years 7 months ago
    Prediction of tissue-specific cis-regulatory modules using Bayesian networks and regression trees
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    Background: In vertebrates, a large part of gene transcriptional regulation is operated by cisregulatory modules. These modules are believed to be regulating much of the tissue-sp...
    Xiaoyu Chen, Mathieu Blanchette
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    BMCBI
    2005
    103views more  BMCBI 2005»
    Many accurate small-discriminatory feature subsets exist in microarray transcript data: biomarker discovery
    13 years 7 months ago
    Many accurate small-discriminatory feature subsets exist in microarray transcript data: biomarker discovery
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    Background: Molecular profiling generates abundance measurements for thousands of gene transcripts in biological samples such as normal and tumor tissues (data points). Given such...
    Leslie Grate
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