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FSTTCS
1998
Springer
14 years 2 months ago
Alternative Computational Models: A Comparison of Biomolecular and Quantum Computation
Molecular Computation (MC) is massively parallel computation where data is stored and processed within objects of molecular size. Biomolecular Computation (BMC) is MC using biotec...
John H. Reif
RECOMB
2000
Springer
14 years 1 months ago
Sequencing-by-hybridization at the information-theory bound: an optimal algorithm
In a recent paper (Preparata et al., 1999) we introduced a novel probing scheme for DNA sequencing by hybridization (SBH). The new gapped-probe scheme combines natural and univers...
Franco P. Preparata, Eli Upfal
RECOMB
2002
Springer
14 years 10 months ago
Significance Of inter-species matches when evolutionary rate varies
We develop techniques to estimate the statistical significance of gap-free alignments between two genomic DNA sequences, using human-mouse alignments as an example. The sequences ...
Jia Li, Webb Miller
ECAL
2005
Springer
14 years 3 months ago
The Genetic Coding Style of Digital Organisms
Recently, all the human genes were identified. But understanding the functions coded in the genes is of course a much harder problem. We are used to view DNA as some sort of a comp...
Philip Gerlee, Torbjörn Lundh
RECOMB
2008
Springer
14 years 10 months ago
Ab Initio Whole Genome Shotgun Assembly with Mated Short Reads
Next Generation Sequencing (NGS) technologies are capable of reading millions of short DNA sequences both quickly and cheaply. While these technologies are already being used for r...
Paul Medvedev, Michael Brudno