Here we identify duplicated genes in five mammalian genomes and classify these duplicates based on the mechanisms by which they were generated. Retrotransposition accounts for at l...
Paul Ryvkin, Jin Jun, Edward Hemphill, Craig Nelso...
Multiple sequence alignment is the most fundamental task in bioinformatics and computational biology. In this paper, we present a new algorithm to conduct multiple sequences align...
Microfluidics-based biochips, also referred to as lab-on-a-chip (LoC), are devices that integrate fluid-handling functions such as sample preparation, analysis, separation, and de...
Abstract. There are several computer programs that align mRNA with its genomic counterpart to determine exon boundaries. Though most of these programs perform such alignment effici...
In the STS-based mapping, we are requested to obtain the correct order of probes in a DNA sequence from a given set of fragments or equivalently a hybridization matrix A. It is wel...