: Ionizing radiation alters DNA strands and mainly creates multiply damaged sites (MDS), e.g. two or more damaged sites within one or two turns of the DNA (10 to 20 base pairs). Th...
Latifa Douali, Matt Ernst, John Miller, Michel Dup...
Using the thermodynamics of DNA melting, a technique is proposed to choose a reaction temperature for the DNA computation that minimizes the potential for mishybridizations. Adlem...
Background: DNA microarrays, which have been increasingly used to monitor mRNA transcripts at a global level, can provide detailed insight into cellular processes involved in resp...
Tao Han, Cathy D. Melvin, Leming M. Shi, William S...
Background: The multitude of motif detection algorithms developed to date have largely focused on the detection of patterns in primary sequence. Since sequence-dependent DNA struc...
Background: DNA melting curve analysis using double-stranded DNA-specific dyes such as SYTO9 produce complex and reproducible melting profiles, resulting in the detection of multi...
John P. Rasmussen, Christopher P. Saint, Paul T. M...