Hidden Markov Models, or HMMs for short, have been recently used in Bioinformatics for the classification of DNA or protein chains, giving rise to what is known as Profile Hidde...
Maternal influence on offspring goes beyond strict nuclear (DNA) inheritance: inherited maternal mRNA, mitochondria, caring and nurturing are all additional sources that affect...
Background: Using microarray and sequencing platforms, a large number of copy number variations (CNVs) have been identified in humans. In practice, because our human genome is a d...
Background: The recognition of functional binding sites in genomic DNA remains one of the fundamental challenges of genome research. During the last decades, a plethora of differe...
Jens Keilwagen, Jan Grau, Stefan Posch, Marc Stric...
Background: Haplotypes extracted from human DNA can be used for gene mapping and other analysis of genetic patterns within and across populations. A fundamental problem is, howeve...