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» DNA Models and Algorithms for NP-Complete Problems
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GECCO
2007
Springer
160views Optimization» more  GECCO 2007»
14 years 1 months ago
Hill climbing on discrete HIFF: exploring the role of DNA transposition in long-term artificial evolution
We show how a random mutation hill climber that does multilevel selection utilizes transposition to escape local optima on the discrete Hierarchical-If-And-Only-If (HIFF) problem....
Susan Khor
GECCO
2006
Springer
165views Optimization» more  GECCO 2006»
13 years 11 months ago
Comparing mathematical models on the problem of network inference
In this paper we address the problem of finding gene regulatory networks from experimental DNA microarray data. We focus on the evaluation of the performance of different mathemat...
Christian Spieth, Nadine Hassis, Felix Streichert
ICDM
2002
IEEE
173views Data Mining» more  ICDM 2002»
14 years 18 days ago
Mining Genes in DNA Using GeneScout
In this paper, we present a new system, called GeneScout, for predicting gene structures in vertebrate genomic DNA. The system contains specially designed hidden Markov models (HM...
Michael M. Yin, Jason Tsong-Li Wang
CPM
2007
Springer
222views Combinatorics» more  CPM 2007»
14 years 1 months ago
Computing Exact p-Value for Structured Motif
Extracting motifs from a set of DNA sequences is important in computational biology. Occurrence probability is a common used statistics to evaluate the statistical significance of...
Jing Zhang, Xi Chen, Ming Li
DASFAA
2003
IEEE
151views Database» more  DASFAA 2003»
14 years 29 days ago
Approximate String Matching in DNA Sequences
Approximate string matching on large DNA sequences data is very important in bioinformatics. Some studies have shown that suffix tree is an efficient data structure for approxim...
Lok-Lam Cheng, David Wai-Lok Cheung, Siu-Ming Yiu