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» DNA Sequence Design Using Templates
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BMCBI
2011
12 years 11 months ago
Combinatorial analysis and algorithms for quasispecies reconstruction using next-generation sequencing
Background: Next-generation sequencing (NGS) offers a unique opportunity for high-throughput genomics and has potential to replace Sanger sequencing in many fields, including de-n...
Mattia C. F. Prosperi, Luciano Prosperi, Alessandr...
BMCBI
2006
91views more  BMCBI 2006»
13 years 7 months ago
Cheminformatics methods for novel nanopore analysis of HIV DNA termini
Background: Channel current feature extraction methods, using Hidden Markov Models (HMMs) have been designed for tracking individual-molecule conformational changes. This informat...
Stephen Winters-Hilt, Matthew Landry, Mark Akeson,...
EMO
2006
Springer
117views Optimization» more  EMO 2006»
13 years 9 months ago
Multiplex PCR Assay Design by Hybrid Multiobjective Evolutionary Algorithm
Abstract. Multiplex Polymerase Chain Reaction (PCR) assay is to amplify multiple target DNAs simultaneously using different primer pairs for each target DNA. Recently, it is widely...
In-Hee Lee, Soo-Yong Shin, Byoung-Tak Zhang
BMCBI
2002
120views more  BMCBI 2002»
13 years 7 months ago
tacg - a grep for DNA
Background: Pattern matching is the core of bioinformatics; it is used in database searching, restriction enzyme mapping, and finding open reading frames. It is done repeatedly ov...
Harry Mangalam
CIBCB
2007
IEEE
14 years 2 months ago
Multiple Sequence Alignment using Fuzzy Logic
—DNA matching is a crucial step in sequence alignment. Since sequence alignment is an approximate matching process there is a need for good approximate algorithms. The process of...
Sara Nasser, Gregory Vert, Monica N. Nicolescu, Al...