Sequence design is a crucial problem in information-based biotechnology such as DNA-based computation. We introduce a simple strategy named template method that systematically gene...
We survey the biochemical constraints useful for the design of DNA code words for DNA computation. We define the DNA/RNA Code Constraint problem and cover biochemistry topics rel...
Background: The program InDeVal was originally developed to help researchers find known regions of insertion/deletion activity (with the exception of isolated single-base indels) ...
Background: A new algorithm for assessing similarity between primer and template has been developed based on the hypothesis that annealing of primer to template is an information ...
In several cases, the DNA sequences of an organism are available in different stages of its evolution and it is desirable to reconstruct the DNA sequence in a previous evolution st...