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» DSIM: A Distance-Based Indexing Method for Genomic Sequences
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BMCBI
2010
120views more  BMCBI 2010»
13 years 7 months ago
Estimating true evolutionary distances under rearrangements, duplications, and losses
Background: The rapidly increasing availability of whole-genome sequences has enabled the study of whole-genome evolution. Evolutionary mechanisms based on genome rearrangements h...
Yu Lin, Vaibhav Rajan, Krister M. Swenson, Bernard...
BMCBI
2008
130views more  BMCBI 2008»
13 years 7 months ago
A database of phylogenetically atypical genes in archaeal and bacterial genomes, identified using the DarkHorse algorithm
Background: The process of horizontal gene transfer (HGT) is believed to be widespread in Bacteria and Archaea, but little comparative data is available addressing its occurrence ...
Sheila Podell, Terry Gaasterland, Eric E. Allen
SISAP
2008
IEEE
166views Data Mining» more  SISAP 2008»
14 years 1 months ago
Approximate Similarity Search in Genomic Sequence Databases Using Landmark-Guided Embedding
Similarity search in sequence databases is of paramount importance in bioinformatics research. As the size of the genomic databases increases, similarity search of proteins in the...
Ahmet Sacan, Ismail Hakki Toroslu
SSDBM
2010
IEEE
220views Database» more  SSDBM 2010»
13 years 11 months ago
Prefix Tree Indexing for Similarity Search and Similarity Joins on Genomic Data
Similarity search and similarity join on strings are important for applications such as duplicate detection, error detection, data cleansing, or comparison of biological sequences....
Astrid Rheinländer, Martin Knobloch, Nicky Ho...
BMCBI
2005
127views more  BMCBI 2005»
13 years 7 months ago
Genomes are covered with ubiquitous 11 bp periodic patterns, the "class A flexible patterns"
Background: The genomes of prokaryotes and lower eukaryotes display a very strong 11 bp periodic bias in the distribution of their nucleotides. This bias is present throughout a g...
Etienne Larsabal, Antoine Danchin