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BMCBI
2005
13 years 7 months ago
2005
Background: Two central problems in computational biology are the determination of the alignment and phylogeny of a set of biological sequences. The traditional approach to this p...
BMCBI
2005
13 years 7 months ago
2005
Background: Protein sequence alignments have become indispensable for virtually any evolutionary, structural or functional study involving proteins. Modern sequence search and com...
BMCBI
2005
13 years 7 months ago
2005
Background: Although DNA microarray technologies are very powerful for the simultaneous quantitative characterization of thousands of genes, the quality of the obtained experiment...
BMCBI
2005
13 years 7 months ago
2005
Background: Cells react to changing intra- and extracellular signals by dynamically modulating complex biochemical networks. Cellular responses to extracellular signals lead to ch...
BMCBI
2005
13 years 7 months ago
2005
Background: The allele frequencies of single-nucleotide polymorphisms (SNPs) are needed to select an optimal subset of common SNPs for use in association studies. Sequence-based m...