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DAWAK
2000
Springer
14 years 1 months ago
COFE: A Scalable Method for Feature Extraction from Complex Objects
Abstract. Feature Extraction, also known as Multidimensional Scaling, is a basic primitive associated with indexing, clustering, nearest neighbor searching and visualization. We co...
Gabriela Hristescu, Martin Farach-Colton
TCBB
2008
122views more  TCBB 2008»
13 years 9 months ago
Mixed Integer Linear Programming for Maximum-Parsimony Phylogeny Inference
Reconstruction of phylogenetic trees is a fundamental problem in computational biology. While excellent heuristic methods are available for many variants of this problem, new adva...
Srinath Sridhar, Fumei Lam, Guy E. Blelloch, R. Ra...
BMCBI
2007
162views more  BMCBI 2007»
13 years 9 months ago
Three-Dimensional Phylogeny Explorer: Distinguishing paralogs, lateral transfer, and violation of "molecular clock" assumption w
Background: Construction and interpretation of phylogenetic trees has been a major research topic for understanding the evolution of genes. Increases in sequence data and complexi...
Namshin Kim, Christopher Lee
BMCBI
2010
136views more  BMCBI 2010»
13 years 9 months ago
Protein structure analysis of mutations causing inheritable diseases. An e-Science approach with life scientist friendly interfa
Background: Many newly detected point mutations are located in protein-coding regions of the human genome. Knowledge of their effects on the protein's 3D structure provides i...
Hanka Venselaar, Tim A. H. te Beek, Remko K. P. Ku...
BMCBI
2008
116views more  BMCBI 2008»
13 years 9 months ago
Gene Ontology annotations: what they mean and where they come from
To address the challenges of information integration and retrieval, the computational genomics community increasingly has come to rely on the methodology of creating annotations o...
David P. Hill, Barry Smith, Monica S. McAndrews-Hi...