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» Data Quality in Genome Databases
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BMCBI
2007
97views more  BMCBI 2007»
13 years 7 months ago
A verification protocol for the probe sequences of Affymetrix genome arrays reveals high probe accuracy for studies in mouse, hu
Background: The Affymetrix GeneChip technology uses multiple probes per gene to measure its expression level. Individual probe signals can vary widely, which hampers proper interp...
Rudi Alberts, Peter Terpstra, Menno Hardonk, Leoni...
BMCBI
2008
85views more  BMCBI 2008»
13 years 7 months ago
SPSmart: adapting population based SNP genotype databases for fast and comprehensive web access
Background: In the last five years large online resources of human variability have appeared, notably HapMap, Perlegen and the CEPH foundation. These databases of genotypes with p...
Jorge Amigo, Antonio Salas, Christopher Phillips, ...
BMCBI
2005
131views more  BMCBI 2005»
13 years 7 months ago
Functional annotation by identification of local surface similarities: a novel tool for structural genomics
Background: Protein function is often dependent on subsets of solvent-exposed residues that may exist in a similar three-dimensional configuration in non homologous proteins thus ...
Fabrizio Ferrè, Gabriele Ausiello, Andreas ...
BMCBI
2006
130views more  BMCBI 2006»
13 years 7 months ago
Spatial normalization of array-CGH data
Background: Array-based comparative genomic hybridization (array-CGH) is a recently developed technique for analyzing changes in DNA copy number. As in all microarray analyses, no...
Pierre Neuvial, Philippe Hupé, Isabel Brito...
ICWE
2007
Springer
14 years 1 months ago
On the Quality of Navigation Models with Content-Modification Operations
Initially, web development methods focused on the generation of read-only web applications for browsing the data stored in relational database systems. Lately, many have evolved to...
Jordi Cabot, Jordi Ceballos, Cristina Gómez