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ISMB
1998
15 years 6 months ago
Advanced Query Mechanisms for Biological Databases
Existing query interfaces for biological databases are either based on fixed forms or textual query languages. Users of a fixed form-based query interface are limited to performin...
I-Min A. Chen, Anthony Kosky, Victor M. Markowitz,...
BMCBI
2007
120views more  BMCBI 2007»
15 years 4 months ago
Re-sampling strategy to improve the estimation of number of null hypotheses in FDR control under strong correlation structures
Background: When conducting multiple hypothesis tests, it is important to control the number of false positives, or the False Discovery Rate (FDR). However, there is a tradeoff be...
Xin Lu, David L. Perkins
BMCBI
2010
117views more  BMCBI 2010»
15 years 4 months ago
Automatic, context-specific generation of Gene Ontology slims
Background: The use of ontologies to control vocabulary and structure annotation has added value to genomescale data, and contributed to the capture and re-use of knowledge across...
Melissa J. Davis, Muhammad Shoaib B. Sehgal, Mark ...
BMCBI
2008
123views more  BMCBI 2008»
15 years 4 months ago
Shape based indexing for faster search of RNA family databases
Background: Most non-coding RNA families exert their function by means of a conserved, common secondary structure. The Rfam data base contains more than five hundred structurally ...
Stefan Janssen, Jens Reeder, Robert Giegerich
CBRMD
2008
167views more  CBRMD 2008»
15 years 4 months ago
Case-based Reasoning for Diagnosis of Stress using Enhanced Cosine and Fuzzy Similarity
Intelligent analysis of heterogeneous data and information sources for efficient decision support presents an interesting yet challenging task in clinical environments. This is par...
Mobyen Uddin Ahmed, Shahina Begum, Peter Funk, Nin...