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BMCBI
2010
178views more  BMCBI 2010»
15 years 2 months ago
Selecting high-dimensional mixed graphical models using minimal AIC or BIC forests
Background: Chow and Liu showed that the maximum likelihood tree for multivariate discrete distributions may be found using a maximum weight spanning tree algorithm, for example K...
David Edwards, Gabriel C. G. de Abreu, Rodrigo Lab...
BMCBI
2010
106views more  BMCBI 2010»
15 years 2 months ago
Multiple structure alignment and consensus identification for proteins
Background: An algorithm is presented to compute a multiple structure alignment for a set of proteins and to generate a consensus (pseudo) protein which captures common substructu...
Ivaylo Ilinkin, Jieping Ye, Ravi Janardan
BMCBI
2008
200views more  BMCBI 2008»
15 years 2 months ago
Defining functional distances over Gene Ontology
Background: A fundamental problem when trying to define the functional relationships between proteins is the difficulty in quantifying functional similarities, even when well-stru...
Angela del Pozo, Florencio Pazos, Alfonso Valencia
BMCBI
2008
105views more  BMCBI 2008»
15 years 2 months ago
A gene pattern mining algorithm using interchangeable gene sets for prokaryotes
Background: Mining gene patterns that are common to multiple genomes is an important biological problem, which can lead us to novel biological insights. When family classification...
Meng Hu, Kwangmin Choi, Wei Su, Sun Kim, Jiong Yan...
COMGEO
2010
ACM
15 years 2 months ago
Approximation algorithm for the kinetic robust K-center problem
Clustering is an important problem and has numerous applications. In this paper we consider an important clustering problem, called the k-center problem. We are given a discrete p...
Sorelle A. Friedler, David M. Mount
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