119 search results - page 12 / 24 » Data-adaptive test statistics for microarray data |
BMCBI
2010
13 years 7 months ago
2010
Background: In many microarray experiments, analysis is severely hindered by a major difficulty: the small number of samples for which expression data has been measured. When one ...
BMCBI
2007
13 years 7 months ago
2007
Background: Gene expression microarray is a powerful technology for genetic profiling diseases and their associated treatments. Such a process involves a key step of biomarker ide...
BMCBI
2007
13 years 7 months ago
2007
Background: Multiple data-analytic methods have been proposed for evaluating gene-expression levels in specific biological pathways, assessing differential expression associated w...
BMCBI
2007
13 years 7 months ago
2007
Background: When conducting multiple hypothesis tests, it is important to control the number of false positives, or the False Discovery Rate (FDR). However, there is a tradeoff be...
BMCBI
2004
13 years 7 months ago
2004
Background: Microarray studies in cancer compare expression levels between two or more sample groups on thousands of genes. Data analysis follows a population-level approach (e.g....