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» Data-adaptive test statistics for microarray data
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BMCBI
2006
127views more  BMCBI 2006»
13 years 7 months ago
Using local gene expression similarities to discover regulatory binding site modules
Background: We present an approach designed to identify gene regulation patterns using sequence and expression data collected for Saccharomyces cerevisae. Our main goal is to rela...
Bartek Wilczynski, Torgeir R. Hvidsten, Andriy Kry...
BMCBI
2008
155views more  BMCBI 2008»
13 years 7 months ago
Extending pathways based on gene lists using InterPro domain signatures
Background: High-throughput technologies like functional screens and gene expression analysis produce extended lists of candidate genes. Gene-Set Enrichment Analysis is a commonly...
Florian Hahne, Alexander Mehrle, Dorit Arlt, Annem...
BMCBI
2010
96views more  BMCBI 2010»
13 years 7 months ago
sdef: an R package to synthesize lists of significant features in related experiments
Background: In microarray studies researchers are often interested in the comparison of relevant quantities between two or more similar experiments, involving different treatments...
Marta Blangiardo, Alberto Cassese, Sylvia Richards...
JCP
2006
157views more  JCP 2006»
13 years 7 months ago
CF-GeNe: Fuzzy Framework for Robust Gene Regulatory Network Inference
Most Gene Regulatory Network (GRN) studies ignore the impact of the noisy nature of gene expression data despite its significant influence upon inferred results. This paper present...
Muhammad Shoaib B. Sehgal, Iqbal Gondal, Laurence ...
BMCBI
2008
97views more  BMCBI 2008»
13 years 7 months ago
MCM-test: a fuzzy-set-theory-based approach to differential analysis of gene pathways
Background: Gene pathway can be defined as a group of genes that interact with each other to perform some biological processes. Along with the efforts to identify the individual g...
Lily R. Liang, Vinay Mandal, Yi Lu, Deepak Kumar