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» Database Searching with DNA and Protein Sequences: An Introd...
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RECOMB
2004
Springer
14 years 7 months ago
Designing multiple simultaneous seeds for DNA similarity search
The challenge of similarity search in massive DNA sequence databases has inspired major changes in BLAST-style alignment tools, which accelerate search by inspecting only pairs of...
Yanni Sun, Jeremy Buhler
BIBE
2005
IEEE
126views Bioinformatics» more  BIBE 2005»
14 years 1 months ago
Suboptimal Alignments Improve the Detection of Weak Homologs in Sequence Database Searches
PSI-BLAST remains one of the popular tools for searching remote homologs in sequence databases. We recently demonstrated that hybrid alignment can function as the alignment core f...
Yuheng Li, Mario Lauria, Ralf Bundschuh
BIBE
2010
IEEE
143views Bioinformatics» more  BIBE 2010»
13 years 8 months ago
The Effect of Sequence Error and Partial Training Data on BLAST Accuracy
- Metagenomics is the study of environmental samples. Because few tools exist for metagenomic analysis, a natural step has been to utilize the popular homology tool, BLAST, to sear...
Steven D. Essinger, Gail L. Rosen
BMCBI
2005
150views more  BMCBI 2005»
13 years 7 months ago
Approaching the taxonomic affiliation of unidentified sequences in public databases - an example from the mycorrhizal fungi
Background: During the last few years, DNA sequence analysis has become one of the primary means of taxonomic identification of species, particularly so for species that are minut...
R. Henrik Nilsson, Erik Kristiansson, Martin Ryber...
BMCBI
2006
108views more  BMCBI 2006»
13 years 7 months ago
RibAlign: a software tool and database for eubacterial phylogeny based on concatenated ribosomal protein subunits
Background: Until today, analysis of 16S ribosomal RNA (rRNA) sequences has been the de-facto gold standard for the assessment of phylogenetic relationships among prokaryotes. How...
Hanno Teeling, Frank Oliver Glöckner