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» Database Searching with DNA and Protein Sequences: An Introd...
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CSB
2003
IEEE
176views Bioinformatics» more  CSB 2003»
14 years 27 days ago
3D Structural Homology Detection via Unassigned Residual Dipolar Couplings
Recognition of a protein’s fold provides valuable information about its function. While many sequence-based homology prediction methods exist, an important challenge remains: tw...
Christopher James Langmead, Bruce Randall Donald
BMCBI
2006
152views more  BMCBI 2006»
13 years 7 months ago
Predicting deleterious nsSNPs: an analysis of sequence and structural attributes
Background: There has been an explosion in the number of single nucleotide polymorphisms (SNPs) within public databases. In this study we focused on non-synonymous protein coding ...
Richard J. B. Dobson, Patricia B. Munroe, Mark J. ...
NAR
2011
176views Computer Vision» more  NAR 2011»
12 years 10 months ago
IUPHAR-DB: new receptors and tools for easy searching and visualization of pharmacological data
The IUPHAR database is an established online reference resource for several important classes of human drug targets and related proteins. As well as providing recommended nomencla...
Joanna L. Sharman, Chidochangu P. Mpamhanga, Micha...
BMCBI
2005
159views more  BMCBI 2005»
13 years 7 months ago
Columba: an integrated database of proteins, structures, and annotations
Background: Structural and functional research often requires the computation of sets of protein structures based on certain properties of the proteins, such as sequence features,...
Silke Trißl, Kristian Rother, Heiko Mül...
JCB
2007
106views more  JCB 2007»
13 years 7 months ago
Clustered Sequence Representation for Fast Homology Search
We present a novel approach to managing redundancy in sequence databanks such as GenBank. We store clusters of near-identical sequences as a representative union-sequence and a se...
Michael Cameron, Yaniv Bernstein, Hugh E. Williams