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» Decomposing Gene Expression into Cellular Processes
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BMCBI
2010
122views more  BMCBI 2010»
13 years 4 months ago
Functional enrichment analyses and construction of functional similarity networks with high confidence function prediction by PF
Background: A new paradigm of biological investigation takes advantage of technologies that produce large high throughput datasets, including genome sequences, interactions of pro...
Troy Hawkins, Meghana Chitale, Daisuke Kihara
BMCBI
2005
201views more  BMCBI 2005»
13 years 9 months ago
Principal component analysis for predicting transcription-factor binding motifs from array-derived data
Background: The responses to interleukin 1 (IL-1) in human chondrocytes constitute a complex regulatory mechanism, where multiple transcription factors interact combinatorially to...
Yunlong Liu, Matthew P. Vincenti, Hiroki Yokota
ISBI
2009
IEEE
14 years 4 months ago
Optimal Illumination Patterns for Fluorescence Tomography
Fluorescence tomography has become increasingly popular for detecting molecular targets for imaging gene expression and other cellular processes in vivo in small animal studies. I...
Joyita Dutta, Sangtae Ahn, Anand A. Joshi, Richard...
BMCBI
2005
124views more  BMCBI 2005»
13 years 9 months ago
Tools enabling the elucidation of molecular pathways active in human disease: Application to Hepatitis C virus infection
Background: The extraction of biological knowledge from genome-scale data sets requires its analysis in the context of additional biological information. The importance of integra...
David J. Reiss, Iliana Avila-Campillo, Vesteinn Th...
AIPS
2003
13 years 11 months ago
A Multi-Agent System-driven AI Planning Approach to Biological Pathway Discovery
As genomic and proteomic data is collected from highthroughput methods on a daily basis, subcellular components are identified and their in vitro behavior is characterized. Howev...
Salim Khan, William Gillis, Carl Schmidt, Keith De...