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» Defining functional distances over Gene Ontology
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BMCBI
2006
146views more  BMCBI 2006»
13 years 11 months ago
GeneTools - application for functional annotation and statistical hypothesis testing
Background: Modern biology has shifted from "one gene" approaches to methods for genomic-scale analysis like microarray technology, which allow simultaneous measurement ...
Vidar Beisvag, Frode K. R. Jünge, Hallgeir Be...
CANDC
2008
ACM
13 years 11 months ago
'Genome order index' should not be used for defining compositional constraints in nucleotide sequences
Background: The Z-curve is a three dimensional representation of DNA sequences proposed over a decade ago and has been extensively applied to sequence segmentation, horizontal gen...
Eran Elhaik, Dan Graur, Kresimir Josic
BMCBI
2005
95views more  BMCBI 2005»
13 years 10 months ago
Commensurate distances and similar motifs in genetic congruence and protein interaction networks in yeast
Background: In a genetic interaction, the phenotype of a double mutant differs from the combined phenotypes of the underlying single mutants. When the single mutants have no growt...
Ping Ye, Brian D. Peyser, Forrest A. Spencer, Joel...
JMLR
2010
133views more  JMLR 2010»
13 years 5 months ago
Hierarchical Cost-Sensitive Algorithms for Genome-Wide Gene Function Prediction
In this work we propose new ensemble methods for the hierarchical classification of gene functions. Our methods exploit the hierarchical relationships between the classes in diffe...
Nicolò Cesa-Bianchi, Giorgio Valentini
ICDE
2007
IEEE
136views Database» more  ICDE 2007»
15 years 7 days ago
Norm, Point, and Distance Estimation Over Multiple Signals Using Max-Stable Distributions
Consider a set of signals fs : {1, . . . , N} [0, . . . , M] appearing as a stream of tuples (i, fs(i)) in arbitrary order of i and s. We would like to devise one pass approximat...
Stilian Stoev, Marios Hadjieleftheriou, George Kol...