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BIOINFORMATICS
2006
124views more  BIOINFORMATICS 2006»
13 years 8 months ago
Probabilistic inference of transcription factor concentrations and gene-specific regulatory activities
Motivation Quantitative estimation of the regulatory relationship between transcription factors and genes is a fundamental stepping stone when trying to develop models of cellular...
Guido Sanguinetti, Neil D. Lawrence, Magnus Rattra...
BMCBI
2007
130views more  BMCBI 2007»
13 years 8 months ago
A model-based optimization framework for the inference of regulatory interactions using time-course DNA microarray expression da
Background: Proteins are the primary regulatory agents of transcription even though mRNA expression data alone, from systems like DNA microarrays, are widely used. In addition, th...
Reuben Thomas, Carlos J. Paredes, Sanjay Mehrotra,...
NAR
2002
89views more  NAR 2002»
13 years 8 months ago
Transcription Regulatory Regions Database (TRRD): its status in 2002
Transcription Regulatory Regions Database (TRRD) is an informational resource containing an integrated description of the gene transcription regulation. An entry of the database c...
Nikolay A. Kolchanov, Elena V. Ignatieva, Elena A....
BMCBI
2007
107views more  BMCBI 2007»
13 years 8 months ago
antiCODE: a natural sense-antisense transcripts database
Background: Natural antisense transcripts (NATs) are endogenous RNA molecules that exhibit partial or complete complementarity to other RNAs, and that may contribute to the regula...
Yifei Yin, Yi Zhao, Jie Wang, Changning Liu, Shugu...
BMCBI
2010
156views more  BMCBI 2010»
13 years 8 months ago
Global screening of potential Candida albicans biofilm-related transcription factors via network comparison
Background: Candida albicans is a commonly encountered fungal pathogen in humans. The formation of biofilm is a major virulence factor in C. albicans pathogenesis and is related t...
Yu-Chao Wang, Chung-Yu Lan, Wen-Ping Hsieh, Luis A...