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BMCBI
2010
135views more  BMCBI 2010»
13 years 7 months ago
HDAPD: a web tool for searching the disease-associated protein structures
Background: The protein structures of the disease-associated proteins are important for proceeding with the structure-based drug design to against a particular disease. Up until n...
Yi-Ruen Lin, Hsin-Yuan Wei, Tsung-Lin Tsai, Thy-Ho...
BMCBI
2006
116views more  BMCBI 2006»
13 years 7 months ago
Integrative missing value estimation for microarray data
Background: Missing value estimation is an important preprocessing step in microarray analysis. Although several methods have been developed to solve this problem, their performan...
Jianjun Hu, Haifeng Li, Michael S. Waterman, Xiang...
BMCBI
2007
141views more  BMCBI 2007»
13 years 7 months ago
A novel approach to detect hot-spots in large-scale multivariate data
Background: Progressive advances in the measurement of complex multifactorial components of biological processes involving both spatial and temporal domains have made it difficult...
Jianhua Wu, Keith M. Kendrick, Jianfeng Feng
JCB
2008
91views more  JCB 2008»
13 years 7 months ago
Computational Quantification of Peptides from LC-MS Data
Liquid chromatography coupled to mass spectrometry (LC-MS) has become a major tool for the study of biological processes. High-throughput LC-MS experiments are frequently conducte...
Ole Schulz-Trieglaff, Rene Hussong, Clemens Gr&oum...
BMCBI
2005
121views more  BMCBI 2005»
13 years 7 months ago
Evaluation of gene importance in microarray data based upon probability of selection
Background: Microarray devices permit a genome-scale evaluation of gene function. This technology has catalyzed biomedical research and development in recent years. As many import...
Li M. Fu, Casey S. Fu-Liu