Background: Many functional proteins have a symmetric structure. Most of these are multimeric complexes, which are made of non-symmetric monomers arranged in a symmetric manner. H...
Background: Microarray compendia profile the expression of genes in a number of experimental conditions. Such data compendia are useful not only to group genes and conditions base...
Katrijn Van Deun, Kathleen Marchal, Willem J. Heis...
Background: A relevant problem in drug design is the comparison and recognition of protein binding sites. Binding sites recognition is generally based on geometry often combined w...
Background: Detection of adaptive amino acid changes in proteins under recent short-term selection is of great interest for researchers studying microevolutionary processes in mic...
Sujay Chattopadhyay, Daniel E. Dykhuizen, Evgeni V...
Background: With the increased availability of high throughput data, such as DNA microarray data, researchers are capable of producing large amounts of biological data. During the...