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BMCBI
2010
136views more  BMCBI 2010»
13 years 8 months ago
Bias correction and Bayesian analysis of aggregate counts in SAGE libraries
Background: Tag-based techniques, such as SAGE, are commonly used to sample the mRNA pool of an organism's transcriptome. Incomplete digestion during the tag formation proces...
Russell L. Zaretzki, Michael A. Gilchrist, William...
BMCBI
2007
114views more  BMCBI 2007»
13 years 8 months ago
Mining and state-space modeling and verification of sub-networks from large-scale biomolecular networks
Background: Biomolecular networks dynamically respond to stimuli and implement cellular function. Understanding these dynamic changes is the key challenge for cell biologists. As ...
Xiaohua Hu, Fang-Xiang Wu
CSB
2003
IEEE
130views Bioinformatics» more  CSB 2003»
14 years 1 months ago
Latent Structure Models for the Analysis of Gene Expression Data
Cluster methods have been successfully applied in gene expression data analysis to address tumor classification. By grouping tissue samples into homogeneous subsets, more systema...
Dong Hua, Dechang Chen, Xiuzhen Cheng, Abdou Youss...
ICDM
2010
IEEE
230views Data Mining» more  ICDM 2010»
13 years 6 months ago
Clustering Large Attributed Graphs: An Efficient Incremental Approach
In recent years, many networks have become available for analysis, including social networks, sensor networks, biological networks, etc. Graph clustering has shown its effectivenes...
Yang Zhou, Hong Cheng, Jeffrey Xu Yu
BMCBI
2006
205views more  BMCBI 2006»
13 years 8 months ago
Application of Petri net based analysis techniques to signal transduction pathways
Background: Signal transduction pathways are usually modelled using classical quantitative methods, which are based on ordinary differential equations (ODEs). However, some diffic...
Andrea Sackmann, Monika Heiner, Ina Koch