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BMCBI
2008
159views more  BMCBI 2008»
13 years 7 months ago
Multivariate hierarchical Bayesian model for differential gene expression analysis in microarray experiments
Background: Identification of differentially expressed genes is a typical objective when analyzing gene expression data. Recently, Bayesian hierarchical models have become increas...
Hongya Zhao, Kwok-Leung Chan, Lee-Ming Cheng, Hong...
BMCBI
2006
159views more  BMCBI 2006»
13 years 7 months ago
MultiSeq: unifying sequence and structure data for evolutionary analysis
Background: Since the publication of the first draft of the human genome in 2000, bioinformatic data have been accumulating at an overwhelming pace. Currently, more than 3 million...
Elijah Roberts, John Eargle, Dan Wright, Zaida Lut...
BMCBI
2006
137views more  BMCBI 2006»
13 years 7 months ago
Bounded search for de novo identification of degenerate cis-regulatory elements
Background: The identification of statistically overrepresented sequences in the upstream regions of coregulated genes should theoretically permit the identification of potential ...
Jonathan M. Carlson, Arijit Chakravarty, Radhika S...
BMCBI
2007
128views more  BMCBI 2007»
13 years 7 months ago
Combining classifiers to predict gene function in Arabidopsis thaliana using large-scale gene expression measurements
Background: Arabidopsis thaliana is the model species of current plant genomic research with a genome size of 125 Mb and approximately 28,000 genes. The function of half of these ...
Hui Lan, Rachel Carson, Nicholas J. Provart, Antho...
BMCBI
2007
110views more  BMCBI 2007»
13 years 7 months ago
Interpretation of multiple probe sets mapping to the same gene in Affymetrix GeneChips
Background: Affymetrix GeneChip technology enables the parallel observations of tens of thousands of genes. It is important that the probe set annotations are reliable so that bio...
Maria A. Stalteri, Andrew P. Harrison