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BMCBI
2010
13 years 7 months ago
2010
Background: Protein-coding gene detection in prokaryotic genomes is considered a much simpler problem than in intron-containing eukaryotic genomes. However there have been reports...
BMCBI
2010
13 years 7 months ago
2010
Background: The construction of interaction networks between proteins is central to understanding the underlying biological processes. However, since many useful relations are exc...
BMCBI
2010
13 years 7 months ago
2010
Background: Human cancer is caused by the accumulation of tumor-specific mutations in oncogenes and tumor suppressors that confer a selective growth advantage to cells. As a conse...
BMCBI
2008
13 years 7 months ago
2008
Background: As the number of non-synonymous single nucleotide polymorphisms (nsSNPs), also known as single amino acid polymorphisms (SAPs), increases rapidly, computational method...
BMCBI
2007
13 years 7 months ago
2007
Background: Analyzing differential-gene-expression data in the context of protein-interaction networks (PINs) yields information on the functional cellular status. PINs can be for...