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BMCBI
2006
120views more  BMCBI 2006»
13 years 7 months ago
Optimizing amino acid substitution matrices with a local alignment kernel
Background: Detecting remote homologies by direct comparison of protein sequences remains a challenging task. We had previously developed a similarity score between sequences, cal...
Hiroto Saigo, Jean-Philippe Vert, Tatsuya Akutsu
BMCBI
2005
150views more  BMCBI 2005»
13 years 7 months ago
Discover protein sequence signatures from protein-protein interaction data
Background: The development of high-throughput technologies such as yeast two-hybrid systems and mass spectrometry technologies has made it possible to generate large protein-prot...
Jianwen Fang, Ryan J. Haasl, Yinghua Dong, Gerald ...
BMCBI
2005
118views more  BMCBI 2005»
13 years 7 months ago
Variation in structural location and amino acid conservation of functional sites in protein domain families
Background: The functional sites of a protein present important information for determining its cellular function and are fundamental in drug design. Accordingly, accurate methods...
Birgit Pils, Richard R. Copley, Jörg Schultz
ASE
2004
137views more  ASE 2004»
13 years 7 months ago
Automatically Restructuring Programs for the Web
The construction of interactive server-side Web applications differs substantially from the construction of traditional interactive programs. In contrast, existing Web programming...
Jacob Matthews, Robert Bruce Findler, Paul T. Grau...
KDD
2010
ACM
300views Data Mining» more  KDD 2010»
13 years 6 months ago
Using data mining techniques to address critical information exchange needs in disaster affected public-private networks
Crisis Management and Disaster Recovery have gained immense importance in the wake of recent man and nature inflicted calamities. A critical problem in a crisis situation is how t...
Li Zheng, Chao Shen, Liang Tang, Tao Li, Steven Lu...