Background: By virtue of their shared ancestry, homologous sequences are similar in their structure and function. Consequently, multiple sequence alignments are routinely used to ...
Daniel R. Caffrey, Paul H. Dana, Vidhya Mathur, Ma...
— The Parallel Resource-Optimal (PRO) computation model was introduced by Gebremedhin et al. [2002] as a framework for the design and analysis of efficient parallel algorithms. ...
The proteins in living organisms perform almost every significant function that governs life. A protein's functionality depends upon its physical structure, which depends on i...
Anish Alex, Jonathan Rose, Ruth Isserlin-Weinberge...
— Despite their success as optimization methods, evolutionary algorithms face many difficulties to design artifacts with complex structures. According to paleontologists, living...
Many characteristics of functional synthetic siRNAs have been identified. Our three-phase algorithm was developed to design siRNA on a wholegenome scale based on these characteris...