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BMCBI
2005
101views more  BMCBI 2005»
13 years 7 months ago
TmaDB: a repository for tissue microarray data
Background: Tissue microarray (TMA) technology has been developed to facilitate large, genome-scale molecular pathology studies. This technique provides a high-throughput method f...
Archana Sharma-Oates, Philip Quirke, David R. West...
BMCBI
2006
112views more  BMCBI 2006»
13 years 7 months ago
GENOMEMASKER package for designing unique genomic PCR primers
Background: The design of oligonucleotides and PCR primers for studying large genomes is complicated by the redundancy of sequences. The eukaryotic genomes are particularly diffic...
Reidar Andreson, Eric Reppo, Lauris Kaplinski, Mai...
NAR
2011
248views Computer Vision» more  NAR 2011»
12 years 10 months ago
NCBI GEO: archive for functional genomics data sets - 10 years on
A decade ago, the Gene Expression Omnibus (GEO) database was established at the National Center for Biotechnology Information (NCBI). The original objective of GEO was to serve as...
Tanya Barrett, Dennis B. Troup, Stephen E. Wilhite...
HIPC
2009
Springer
13 years 4 months ago
Comparing the performance of clusters, Hadoop, and Active Disks on microarray correlation computations
Abstract--Microarray-based comparative genomic hybridization (aCGH) offers an increasingly fine-grained method for detecting copy number variations in DNA. These copy number variat...
Jeffrey A. Delmerico, Nathanial A. Byrnes, Andrew ...
BMCBI
2010
102views more  BMCBI 2010»
13 years 7 months ago
Quantized correlation coefficient for measuring reproducibility of ChIP-chip data
Background: Chromatin immunoprecipitation followed by microarray hybridization (ChIP-chip) is used to study protein-DNA interactions and histone modifications on a genome-scale. T...
Shouyong Peng, Mitzi I. Kuroda, Peter J. Park