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» Designing seeds for similarity search in genomic DNA
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CIKM
2009
Springer
13 years 11 months ago
Suffix trees for very large genomic sequences
A suffix tree is a fundamental data structure for string searching algorithms. Unfortunately, when it comes to the use of suffix trees in real-life applications, the current metho...
Marina Barsky, Ulrike Stege, Alex Thomo, Chris Upt...
BMCBI
2006
92views more  BMCBI 2006»
13 years 8 months ago
A jumping profile Hidden Markov Model and applications to recombination sites in HIV and HCV genomes
Background: Jumping alignments have recently been proposed as a strategy to search a given multiple sequence alignment A against a database. Instead of comparing a database sequen...
Anne-Kathrin Schultz, Ming Zhang, Thomas Leitner, ...
BMCBI
2005
84views more  BMCBI 2005»
13 years 7 months ago
Information theory-based algorithm for in silico prediction of PCR products with whole genomic sequences as templates
Background: A new algorithm for assessing similarity between primer and template has been developed based on the hypothesis that annealing of primer to template is an information ...
Youfang Cao, Lianjie Wang, Kexue Xu, Chunhai Kou, ...
BMCBI
2010
111views more  BMCBI 2010»
13 years 8 months ago
Dynamic probe selection for studying microbial transcriptome with high-density genomic tiling microarrays
Background: Current commercial high-density oligonucleotide microarrays can hold millions of probe spots on a single microscopic glass slide and are ideal for studying the transcr...
Hedda Høvik, Tsute Chen
NAR
2011
248views Computer Vision» more  NAR 2011»
12 years 10 months ago
NCBI GEO: archive for functional genomics data sets - 10 years on
A decade ago, the Gene Expression Omnibus (GEO) database was established at the National Center for Biotechnology Information (NCBI). The original objective of GEO was to serve as...
Tanya Barrett, Dennis B. Troup, Stephen E. Wilhite...