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BMCBI
2008
77views more  BMCBI 2008»
13 years 7 months ago
SeqAn An efficient, generic C++ library for sequence analysis
Background: The use of novel algorithmic techniques is pivotal to many important problems in life science. For example the sequencing of the human genome [1] would not have been p...
Andreas Döring, David Weese, Tobias Rausch, K...
BMCBI
2006
153views more  BMCBI 2006»
13 years 7 months ago
Discovery of time-delayed gene regulatory networks based on temporal gene expression profiling
Background: It is one of the ultimate goals for modern biological research to fully elucidate the intricate interplays and the regulations of the molecular determinants that prope...
Xia Li, Shaoqi Rao, Wei Jiang, Chuanxing Li, Yun X...
BMCBI
2006
87views more  BMCBI 2006»
13 years 7 months ago
Prediction of indirect interactions in proteins
Background: Both direct and indirect interactions determine molecular recognition of ligands by proteins. Indirect interactions can be defined as effects on recognition controlled...
Peteris Prusis, Staffan Uhlén, Ramona Petro...
BMCBI
2006
126views more  BMCBI 2006»
13 years 7 months ago
A joint model of regulatory and metabolic networks
Background: Gene regulation and metabolic reactions are two primary activities of life. Although many works have been dedicated to study each system, the coupling between them is ...
Chen-Hsiang Yeang, Martin Vingron
BMCBI
2006
141views more  BMCBI 2006»
13 years 7 months ago
The use of concept maps during knowledge elicitation in ontology development processes - the nutrigenomics use case
Background: Incorporation of ontologies into annotations has enabled 'semantic integration' of complex data, making explicit the knowledge within a certain field. One of...
Alexander García Castro, Philippe Rocca-Ser...