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BMCBI
2010
13 years 8 months ago
2010
Background: Multiplex Ligation-Dependent Probe Amplification (MLPA) is an application that can be used for the detection of multiple chromosomal aberrations in a single experiment...
BMCBI
2007
13 years 8 months ago
2007
Background: Success of metabolomics as the phenotyping platform largely depends on its ability to detect various sources of biological variability. Removal of platform-specific so...
BMCBI
2010
13 years 8 months ago
2010
Background: Many newly detected point mutations are located in protein-coding regions of the human genome. Knowledge of their effects on the protein's 3D structure provides i...
BMCBI
2008
13 years 8 months ago
2008
Background: Proteomic profiling using mass spectrometry (MS) is one of the most promising methods for the analysis of complex biological samples such as urine, serum and tissue fo...
BMCBI
2005
13 years 8 months ago
2005
Background: The SH3 domain family is one of the most representative and widely studied cases of so-called Peptide Recognition Modules (PRM). The polyproline II motif PxxP that gen...