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» Detecting multivariate differentially expressed genes
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NAR
2010
123views more  NAR 2010»
13 years 2 months ago
Discovering causal signaling pathways through gene-expression patterns
High-throughput gene-expression studies result in lists of differentially expressed genes. Most current meta-analyses of these gene lists include searching for significant members...
Jignesh R. Parikh, Bertram Klinger, Yu Xia, Jarrod...
BMCBI
2010
277views more  BMCBI 2010»
13 years 7 months ago
PCA2GO: a new multivariate statistics based method to identify highly expressed GO-Terms
Background: Several tools have been developed to explore and search Gene Ontology (GO) databases allowing efficient GO enrichment analysis and GO tree visualization. Nevertheless,...
Marc Bruckskotten, Mario Looso, Franz Cemic, Anne ...
BMCBI
2010
96views more  BMCBI 2010»
13 years 7 months ago
A statistical framework for differential network analysis from microarray data
Background: It has been long well known that genes do not act alone; rather groups of genes act in consort during a biological process. Consequently, the expression levels of gene...
Ryan Gill, Somnath Datta, Susmita Datta
BMCBI
2006
104views more  BMCBI 2006»
13 years 7 months ago
Semi-supervised discovery of differential genes
Background: Various statistical scores have been proposed for evaluating the significance of genes that may exhibit differential expression between two or more controlled conditio...
Shigeyuki Oba, Shin Ishii
BMCBI
2006
86views more  BMCBI 2006»
13 years 7 months ago
Identification of QTLs controlling gene expression networks defined a priori
Background: Gene expression microarrays allow the quantification of transcript accumulation for many or all genes in a genome. This technology has been utilized for a range of inv...
Daniel J. Kliebenstein, Marilyn A. L. West, Hans v...