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BMCBI
2011
12 years 10 months ago
PRIN, a predicted rice interactome network
Background: Protein-protein interactions play a fundamental role in elucidating the molecular mechanisms of biomolecular function, signal transductions and metabolic pathways of l...
Haibin Gu, Pengcheng Zhu, Yinming Jiao, Yijun Meng...
BMCBI
2008
120views more  BMCBI 2008»
13 years 7 months ago
A protein interaction based model for schizophrenia study
Background: Schizophrenia is a complex disease with multiple factors contributing to its pathogenesis. In addition to environmental factors, genetic factors may also increase susc...
Pei-Chun Hsu, Ueng-Cheng Yang, Kuan-Hui Shih, Chih...
BMCBI
2005
253views more  BMCBI 2005»
13 years 7 months ago
The Use of Edge-Betweenness Clustering to Investigate Biological Function in Protein Interaction Networks
Background: This paper describes an automated method for finding clusters of interconnected proteins in protein interaction networks and retrieving protein annotations associated ...
Ruth Dunn, Frank Dudbridge, Christopher M. Sanders...
BIRD
2008
Springer
163views Bioinformatics» more  BIRD 2008»
13 years 9 months ago
Multi-functional Protein Clustering in PPI Networks
Abstract. Protein-Protein Interaction (PPI) networks contain valuable information for the isolation of groups of proteins that participate in the same biological function. Many pro...
Clara Pizzuti, Simona E. Rombo
CSB
2005
IEEE
180views Bioinformatics» more  CSB 2005»
14 years 21 days ago
Functional Modularity in a Large-Scale Mammalian Molecular Interaction Network
The Ingenuity™ Pathways Knowledge Base (IPKB) contains over one million findings manually curated from the scientific literature. Highly-structured content from the IPKB forms...
Andreas Kramer, Daniel R. Richards, James O. Bowlb...