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BMCBI
2006
112views more  BMCBI 2006»
13 years 7 months ago
GENOMEMASKER package for designing unique genomic PCR primers
Background: The design of oligonucleotides and PCR primers for studying large genomes is complicated by the redundancy of sequences. The eukaryotic genomes are particularly diffic...
Reidar Andreson, Eric Reppo, Lauris Kaplinski, Mai...
BMCBI
2005
122views more  BMCBI 2005»
13 years 7 months ago
Quantitative analysis of EGR proteins binding to DNA: assessing additivity in both the binding site and the protein
Background: Recognition codes for protein-DNA interactions typically assume that the interacting positions contribute additively to the binding energy. While this is known to not ...
Jiajian Liu, Gary D. Stormo
BMCBI
2007
158views more  BMCBI 2007»
13 years 7 months ago
Penalized likelihood for sparse contingency tables with an application to full-length cDNA libraries
Background: The joint analysis of several categorical variables is a common task in many areas of biology, and is becoming central to systems biology investigations whose goal is ...
Corinne Dahinden, Giovanni Parmigiani, Mark C. Eme...
BMCBI
2008
163views more  BMCBI 2008»
13 years 7 months ago
The Annotation, Mapping, Expression and Network (AMEN) suite of tools for molecular systems biology
Background: High-throughput genome biological experiments yield large and multifaceted datasets that require flexible and user-friendly analysis tools to facilitate their interpre...
Frédéric Chalmel, Michael Primig
MICS
2010
81views more  MICS 2010»
13 years 6 months ago
Tactics for Hierarchical Proof
Abstract. There is something of a discontinuity at the heart of popular tactical theorem provers. Low-level, fully-checked mechanical proofs are large trees consisting of primitive...
David Aspinall, Ewen Denney, Christoph Lüth