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» Determining gene expression on a single pair of microarrays
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BMCBI
2008
129views more  BMCBI 2008»
13 years 7 months ago
EMAAS: An extensible grid-based Rich Internet Application for microarray data analysis and management
Background: Microarray experimentation requires the application of complex analysis methods as well as the use of non-trivial computer technologies to manage the resultant large d...
Geraint Barton, J. C. Abbott, Norie Chiba, D. W. H...
BMCBI
2006
115views more  BMCBI 2006»
13 years 7 months ago
SimArray: a user-friendly and user-configurable microarray design tool
Background: Microarrays were first developed to assess gene expression but are now also used to map protein-binding sites and to assess allelic variation between individuals. Rega...
Richard P. Auburn, Roslin R. Russell, Bettina Fisc...
BMCBI
2006
82views more  BMCBI 2006»
13 years 7 months ago
Prediction of a key role of motifs binding E2F and NR2F in down-regulation of numerous genes during the development of the mouse
Background: We previously demonstrated that gene expression profiles during neuronal differentiation in vitro and hippocampal development in vivo were very similar, due to a conse...
Michal Dabrowski, Stein Aerts, Bozena Kaminska
BMCBI
2011
13 years 2 months ago
Sequential Interim Analyses of Survival Data in DNA Microarray Experiments
Background: Discovery of biomarkers that are correlated with therapy response and thus with survival is an important goal of medical research on severe diseases, e.g. cancer. Freq...
Andreas Leha, Tim Beißbarth, Klaus Jung
BMCBI
2007
138views more  BMCBI 2007»
13 years 7 months ago
A systematic approach to detecting transcription factors in response to environmental stresses
Background: Eukaryotic cells have developed mechanisms to respond to external environmental or physiological changes (stresses). In order to increase the activities of stress-prot...
Li-Hsieh Lin, Hsiao-Ching Lee, Wen-Hsiung Li, Bor-...