11462 search results - page 2255 / 2293 » Developing Application-Centric Methods |
131
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BMCBI
2008
15 years 2 months ago
2008
Background: The identification of transcription factor binding sites is difficult since they are only a small number of nucleotides in size, resulting in large numbers of false po...
108
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BMCBI
2007
15 years 2 months ago
2007
Background: RNA metabolism, through 'combinatorial splicing', can generate enormous structural diversity in the proteome. Alternative domains may interact, however, with...
111
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BMCBI
2008
15 years 2 months ago
2008
Background: As a rule, peptides are more flexible and unstructured than proteins with their substantial stabilizing hydrophobic cores. Nevertheless, a few stably folding peptides ...
117
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BMCBI
2007
15 years 2 months ago
2007
Background: Currently, there exists tens of different microbial and eukaryotic metabolic reconstructions (e.g., Escherichia coli, Saccharomyces cerevisiae, Bacillus subtilis) with...
109
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BMCBI
2008
15 years 2 months ago
2008
Background: Drug discovery and chemical biology are exceedingly complex and demanding enterprises. In recent years there are been increasing awareness about the importance of pred...