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BMCBI
2006
106views more  BMCBI 2006»
13 years 7 months ago
Prediction of the functional class of metal-binding proteins from sequence derived physicochemical properties by support vector
Metal-binding proteins play important roles in structural stability, signaling, regulation, transport, immune response, metabolism control, and metal homeostasis. Because of their...
H. H. Lin, L. Y. Han, H. L. Zhang, C. J. Zheng, B....
JBI
2006
13 years 7 months ago
Phylogenetics by likelihood: Evolutionary modeling as a tool for understanding the genome
Molecular evolutionary studies provide a means of investigating how cells function and how organisms adapt to their environment. The products of evolutionary studies provide medic...
Carolin Kosiol, Lee Bofkin, Simon Whelan
JNCA
2006
86views more  JNCA 2006»
13 years 7 months ago
Real-time data attack isolation for commercial database applications
Traditional database security mechanisms are very limited in defending against data attacks. Authorized but malicious transactions can make a database useless by impairing its int...
Peng Liu, Hai Wang, Lunquan Li
ICASSP
2011
IEEE
12 years 11 months ago
Biological pathway inference using manifold embedding
Disease occurs due to aberrant modulation of biological pathways. Identification of activated gene pathways from gene expression data is an important problem. In this work, we de...
Arvind Rao, Alfred O. Hero
BMCBI
2010
141views more  BMCBI 2010»
13 years 7 months ago
CIG-DB: the database for human or mouse immunoglobulin and T cell receptor genes available for cancer studies
Background: Immunoglobulin (IG or antibody) and the T-cell receptor (TR) are pivotal proteins in the immune system of higher organisms. In cancer immunotherapy, the immune respons...
Yoji Nakamura, Tomoyoshi Komiyama, Motoki Furue, T...