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EJIS
2010
112views more  EJIS 2010»
13 years 7 months ago
Toward an 'IT Conflict-Resistance Theory': action research during IT pre-implementation
Most empirical research on users' resistance toward Information Technology (IT) has been conducted after implementation of IT in organisations. Little research has been done ...
Regis Meissonier, Emmanuel Houzé
BMCBI
2006
184views more  BMCBI 2006»
13 years 7 months ago
PathSys: integrating molecular interaction graphs for systems biology
Background: The goal of information integration in systems biology is to combine information from a number of databases and data sets, which are obtained from both high and low th...
Michael Baitaluk, Xufei Qian, Shubhada Godbole, Al...
BMCBI
2006
138views more  BMCBI 2006»
13 years 7 months ago
Determination of strongly overlapping signaling activity from microarray data
Background: As numerous diseases involve errors in signal transduction, modern therapeutics often target proteins involved in cellular signaling. Interpretation of the activity of...
Ghislain Bidaut, Karsten Suhre, Jean-Michel Claver...
BMCBI
2007
132views more  BMCBI 2007»
13 years 7 months ago
Dependence of paracentric inversion rate on tract length
Background: We develop a Bayesian method based on MCMC for estimating the relative rates of pericentric and paracentric inversions from marker data from two species. The method al...
Thomas L. York, Richard Durrett, Rasmus Nielsen
BMCBI
2007
141views more  BMCBI 2007»
13 years 7 months ago
A novel approach to detect hot-spots in large-scale multivariate data
Background: Progressive advances in the measurement of complex multifactorial components of biological processes involving both spatial and temporal domains have made it difficult...
Jianhua Wu, Keith M. Kendrick, Jianfeng Feng