Background: Gene clustering has been widely used to group genes with similar expression pattern in microarray data analysis. Subsequent enrichment analysis using predefined gene s...
Tae-Min Kim, Yeun-Jun Chung, Mun-Gan Rhyu, Myeong ...
Background: Eukaryotic cells have developed mechanisms to respond to external environmental or physiological changes (stresses). In order to increase the activities of stress-prot...
Background: Metabolic Flux Analysis (MFA) based on isotope labeling experiments (ILEs) is a widely established tool for determining fluxes in metabolic pathways. Isotope labeling ...
Michael Weitzel, Wolfgang Wiechert, Katharina N&ou...
Background: The simulation of metabolic networks in quantitative systems biology requires the assignment of enzymatic kinetic parameters. Experimentally determined values are ofte...
Razif R. Gabdoulline, Matthias Stein, Rebecca C. W...
Background: Transcription factors (TFs) are key regulatory proteins that enhance or repress the transcriptional rate of their target genes by binding to specific promoter regions ...