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BMCBI
2006
100views more  BMCBI 2006»
15 years 4 months ago
Empirical array quality weights in the analysis of microarray data
Background: Assessment of array quality is an essential step in the analysis of data from microarray experiments. Once detected, less reliable arrays are typically excluded or &qu...
Matthew E. Ritchie, Dileepa S. Diyagama, Jody Neil...
BMCBI
2010
118views more  BMCBI 2010»
15 years 4 months ago
Testing for mean and correlation changes in microarray experiments: an application for pathway analysis
Background: Microarray experiments examine the change in transcript levels of tens of thousands of genes simultaneously. To derive meaningful data, biologists investigate the resp...
Mayer Alvo, Zhongzhu Liu, Andrew Williams, Carole ...
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DAGSTUHL
2009
15 years 5 months ago
Median Topographic Maps for Biomedical Data Sets
Abstract. Median clustering extends popular neural data analysis methods such as the self-organizing map or neural gas to general data structures given by a dissimilarity matrix on...
Barbara Hammer, Alexander Hasenfuss, Fabrice Rossi
BMCBI
2010
94views more  BMCBI 2010»
15 years 4 months ago
A comparative study of conservation and variation scores
Background: Conservation and variation scores are used when evaluating sites in a multiple sequence alignment, in order to identify residues critical for structure or function. A ...
Fredrik Johansson, Hiroyuki Toh
BMCBI
2010
142views more  BMCBI 2010»
15 years 2 months ago
Comparison of Beta-value and M-value methods for quantifying methylation levels by microarray analysis
Background: High-throughput profiling of DNA methylation status of CpG islands is crucial to understand the epigenetic regulation of genes. The microarray-based Infinium methylati...
Pan Du, Xiao Zhang, Chiang-Ching Huang, Nadereh Ja...